While clicking through various links on the awesome HTML5 Rocks site, I stumbled upon HTML5 Boilerplate. This site is a godsend for anyone needing a starting point for writing a modern web interface. This is a Paul Irish project, so you can be assured the code is good and the comments will be humorous. If you have a free evening, I strongly recommend grabbing the code and taking a look how it should be done.
HTML5 Boilerplate gets five stars of Newfound Coolness.